Imagine that any false step, fall or blow, may result in a complicated fracture.
There are persons that live slope of each movement they make, since a small error may overcome in a serious problem.
The Osteogenesis imperfecta (OI) is a genetic condition that, in diverse degrees, affects one of each 20 thousand person. Also known as the bone of glass disease, there is no cure for it, but who suffer it undergo a series of therapies that allow them to live with more normality.
This condition even went to the cinema in the movie the Protected, in which the character of Samuel L. Jackson suffers Osteogenesis Imperfecta. Several television series also had shown cases.
What causes Osteogenesis Imperfect
Osteogenesis imperfecta is genetic disease of hereditary origin and is present since intrauterine development stage. Ii is common that babies suffering it are born with fractures.
An important amount of cases is due to hereditary factors though a dominant gene that possesses a mutation, it is sufficient that only one parent must be the carrier. A less patient percentage, suffers OI by a spontaneous genetic mutation.
The Osteogenesis imperfecta, prevents the formation of hard bone, since the organism of who suffer it possess insufficient type I collagen, or this is of inferior quality from normal.
The collagen is the framework through which bones are developed and this framework is not hard enough, the bones won’t be either. Not all patients with OI are the same.
Types of Osteogenesis Imperfecta
There are eight classifications for Osteogenesis imperfecta, which goes from soft shapes to those incompatibles with life. The most common is Type I, which also offers the best prognosis.
Persons who suffer OI in grade I will suffer several fractures, especially when reaching puberty. Persons, who suffer OI in grade I, will suffer several fractures, especially when reaching puberty. Their vertebral column is curved and, the articulations will dislocate very easily.
They are short stature, poor muscular tone and, those who suffer it used to have discoloration of the white of the eye, which is blue or gray. An important percentage will have hearing problems.
In Osteogenesis Imperfecta Type I, the body produces collagen of good quality, but in insufficient amount. The same thing happens with types III, IV, V, all compatible with life, but varies in gravity.
Who suffers Osteogenesis Imperfecta of Type II, VII, has few possibilities of survival after birth and, the remaining of the classifications, are really sub types of the above.
Treatment for Osteogenesis Imperfecta
As we said before, no cure exist for crystal bone disease, but patients benefit with treatments that go from surgery to medications, physical therapy or crotches and wheel chair usage.
Osteogenesis Imperfecta is not an excuse to develop physical activity. Several para Olympics’ athletes suffer it, as well as musicians and actors, demonstrating that is possible to live with this disability.